Recently accepted paper in Eur Urol

Dapoxetine for the Treatment of Premature Ejaculation: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial in 22 Countries
Buvat J, Tesfaye F, Rothman M, Rivas DA, Giuliano F.
Eur Urol. 2009 Apr; 55(4):957-67

December 10th - 2008

Best presentation at ESSM-ISSM

Pelvipharm has received an award on the “Best presentation on FSD (preclinical)” at the Joint meeting of the European and International Societies for Sexual Medecine in Brussels, Belgium (10 december 2008).

December 8th - 2008

ESSM Award of Excellence

Delphine Behr-Roussel from Pelvipharm has received the ESSM Award of Excellence during the joint meeting of the European and International Societies for Sexual Medecine in Brussels, Belgium (8 december 2008).

December 7th - 2008

Presentations at the ESSM-ISSM 2008

Pelvipharm at the ESSM-ISSM (Joint meeting of the European and International Societies for Sexual Medecine) in Brussels, Belgium, 7 - 11 december 2008.

Delphine Behr-Roussel from Pelvipharm delivered the ESSM Award of Excellence Lecture on "Endothelial dysfunction: a unifying alteration in the pathogenesis of ED, a common therapeutic target ?"

Aren Borgdorff from Pelvipharm delivered the ESSM Grant Lecture on "Investigation of the functional and pharmacological properties of the spinal generator of ejaculation".

Pelvipharm also presented 4 oral communications:

"Neuroanatomical distribution of the melanocortin-4 receptors in male and female rodent central nervous system"

"Immunohistochemical characterization of the rodent brain neurons involved in the efferent control of the clitoris and the vagina"

"Alteration of the spinal command of ejaculation in rapid ejaculating rats"

"Prevalence of male sexual dysfunction among men consulting urologists : findings of a national survey"

March 26th - 2008

Presentations at the EAU 2008

Pelvipharm at the EAU (European Association of Uroloy) in Milan, Italy, 26-29 March 2008.

Pelvipharm presented 12 Posters:

"Combination of alfuzosin and tadalafil exerts additive relaxant effect on human prostate"
"Combination of alfuzosin and tadalafil exerts an additive enhancing effect on norepinephrine-induced relaxation of pre-contracted human detrusor smooth muscle"
"Effect of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients"
"Sildenafil relaxes human detrusor by cyclic GMP-independent signalling pathways"
"Ejaculation elicited by microstimulation of lumbar spinothalamic neurons"
"Brain oxytocin receptor blockade inhibits pharmacologically-induced sexual responses in anaesthetised male rats"
"PDE5 gene expression and relaxant effects of vardenafil in male and female human and rat detrusor muscle"
"Selective antagonism of dopamine D3 receptor specifically inhibits the expulsion phase of ejaculation in anaesthetised male rats"
"Impact of premature ejaculation (PE) on female partners: results from a 5-country european observational study"
"Local delivery of thyroid hormones within neuroregenerative guide enhances erectile function recovery in a rat model of cavernous nerve injury"
"Improvement in sexual functioning of female partners of men with premature ejaculation (PE) treated with dapoxetine (DPX)"
"Lack of withdrawal syndrome or effects on anxiety with dapoxetine (DPX) for the treatment of premature ejaculation: results from 2 phase III trials"

March 29th - 2008

Best Poster Prizes at the EAU

At the EAU meeting in Milan, Italy, 3 Pelvipharm's communication received the Best Poster Prize (26-29 march 2008), and one communication received the "Second Best Poster Prize".

"Combination of alfuzosin and tadalafil exerts additive relaxant effect on human prostate” received the “Best Poster Prize" of its session.
"PDE5 gene expression and relaxant effects of vardenafil in male and female human and rat detrusor muscle" received the “Best Poster Prize” of its session.
"Effect of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients" received the “Best Poster Prize” of its session.
"Combination of alfuzosin and tadalafil exerts an additive enhancing effect on norepinephrine-induced relaxation of pre-contracted human detrusor smooth muscle" received the “Second Best Poster Prize” of its session.