December 19th - 2008
Recently accepted paper in Eur Urol
Dapoxetine for the Treatment of Premature Ejaculation: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial in 22 Countries
Buvat J, Tesfaye F, Rothman M, Rivas DA, Giuliano F.
Eur Urol. 2009 Apr; 55(4):957-67
December 10th - 2008
Best presentation at ESSM-ISSM
Pelvipharm has received an award on the Best presentation on FSD (preclinical) at the Joint meeting of the European and International Societies for Sexual Medecine in Brussels, Belgium (10 december 2008).
December 8th - 2008
ESSM Award of Excellence
Delphine Behr-Roussel from Pelvipharm has received the ESSM Award of Excellence during the joint meeting of the European and International Societies for Sexual Medecine in Brussels, Belgium (8 december 2008).
December 7th - 2008
Presentations at the ESSM-ISSM 2008
Delphine Behr-Roussel from Pelvipharm delivered the ESSM Award of Excellence Lecture on "Endothelial dysfunction: a unifying alteration in the pathogenesis of ED, a common therapeutic target ?"
Aren Borgdorff from Pelvipharm delivered the ESSM Grant Lecture on "Investigation of the functional and pharmacological properties of the spinal generator of ejaculation".
- Pelvipharm also presented 4 oral communications:
- "Neuroanatomical distribution of the melanocortin-4 receptors in male and female rodent central nervous system"
- "Immunohistochemical characterization of the rodent brain neurons involved in the efferent control of the clitoris and the vagina"
- "Alteration of the spinal command of ejaculation in rapid ejaculating rats"
- "Prevalence of male sexual dysfunction among men consulting urologists : findings of a national survey"
March 26th - 2008
Presentations at the EAU 2008
Pelvipharm at the EAU (European Association of Uroloy) in Milan, Italy, 26-29 March 2008.
Pelvipharm presented 12 Posters:
- "Combination of alfuzosin and tadalafil exerts additive relaxant effect on human prostate"
- "Combination of alfuzosin and tadalafil exerts an additive enhancing effect on norepinephrine-induced relaxation of pre-contracted human detrusor smooth muscle"
- "Effect of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients"
- "Sildenafil relaxes human detrusor by cyclic GMP-independent signalling pathways"
- "Ejaculation elicited by microstimulation of lumbar spinothalamic neurons"
- "Brain oxytocin receptor blockade inhibits pharmacologically-induced sexual responses in anaesthetised male rats"
- "PDE5 gene expression and relaxant effects of vardenafil in male and female human and rat detrusor muscle"
- "Selective antagonism of dopamine D3 receptor specifically inhibits the expulsion phase of ejaculation in anaesthetised male rats"
- "Impact of premature ejaculation (PE) on female partners: results from a 5-country european observational study"
- "Local delivery of thyroid hormones within neuroregenerative guide enhances erectile function recovery in a rat model of cavernous nerve injury"
- "Improvement in sexual functioning of female partners of men with premature ejaculation (PE) treated with dapoxetine (DPX)"
- "Lack of withdrawal syndrome or effects on anxiety with dapoxetine (DPX) for the treatment of premature ejaculation: results from 2 phase III trials"
March 29th - 2008
Best Poster Prizes at the EAU
At the EAU meeting in Milan, Italy, 3 Pelvipharm's communication received the Best Poster Prize (26-29 march 2008), and one communication received the "Second Best Poster Prize".
- "Combination of alfuzosin and tadalafil exerts additive relaxant effect on human prostate received the Best Poster Prize" of its session.
- "PDE5 gene expression and relaxant effects of vardenafil in male and female human and rat detrusor muscle" received the Best Poster Prize of its session.
- "Effect of potassium channel modulators on myogenic spontaneous phasic
contractile activity in human detrusor from neurogenic patients"
received the Best Poster Prize of its session.
- "Combination of alfuzosin and tadalafil exerts an additive enhancing effect on norepinephrine-induced relaxation of pre-contracted human detrusor smooth muscle" received the Second Best Poster Prize of its session.
November 17th - 2008
Recently accepted paper in J Sex Med
Combination of doxazosin and sildenafil exerts an additive relaxing effect compared with each compound alone on human cavernosal and prostatic tissue.
Oger S, Behr-Roussel D, Gorny D, Lecoz O, Lebret T, Denoux Y, Faix A, Leriche A, Wayman C, Alexandre L, Giuliano F.
J Sex Med. 2009 Mar; Vol 6, Issue 3, p: 836-47.
November 3rd - 2008
Recently accepted paper in Int J Impot Res
New horizons in erectile and endothelial dysfunction research and therapies
Giuliano F.
Int J Impot Res. 2008 Dec; 20 Suppl 2:S2-8
September 30th - 2008
Recently accepted paper in BJU Int
Medical treatments for benign prostatic hyperplasia and sexual function.
Giuliano F.
BJU Int. 2008 Nov;102 Suppl 2:8-12.
September 25th - 2008
Recently accepted paper in J Sex Med
Role of the neurokinin-1 receptors in ejaculation in anesthetized rats.
Clement P, Peeters M, Bernabe J, Laurin M, Alexandre L, Giuliano F.
J Sex Med. 2009 Jan;6(1):126-34.
May 17th - 2008
Presentations at the AUA 2008
Pelvipharm at the AUA (American Urological Association) in Orlando, USA, 1722 may2008.
Pelvipharm presented 11 abstracts :
- 2 oral communications :
- "Benefit of a combination of alfuzosin and tadalafil on norepinephrine-induced relaxation of pre-contracted human detrusor smooth muscle" selected for the BPH Highlights session and
- "PDE5 gene expression and relaxant effects of vardenafil in male and female human and rat detrusor muscle" selected for the LUTS/BPH Take Home message session
- 9 Posters :
- "Signaling pathways involved in sildenafil-induced relaxation of human detrusor"
- "KATP but not BKCa channels are involved in the regulation of myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients"
- "Effects of antibiotic therapy on the appearance of the abnormal micturition reflex after spinal cord injury in rats"
- "Ejaculation elicited by microstimulation of lumbar spinothalamic neurons"
- "Neuroregeneration guidance and erectile function recovery with a guide filled in triiodothyronine on a rat model of cavernous nerve injury"
- "Brain oxytocin receptor blockade inhibits pharmacologically-induced sexual responses in anaesthetised male rats"
- "A selective neurokinin-1 receptor antagonist modulates pharmacologically-induced ejaculation in anaesthetised male rats"
- "Improvement in Sexual Satisfaction of Female Partners of Men With Premature Ejaculation (PE) Treated With Dapoxetine (DPX); Additive relaxant effect of a combination of alfuzosin and tadalafil on human prostate"
